Treatment of Erectile Dysfunction -Pharmacology [87soFFXdfmh]

Treatment of Erectile Dysfunction -Pharmacology [87soFFXdfmh]

| 1h 28m 28s | Video has closed captioning.

Drugs licensed for the treatment of erectile dysfunction include 1.Phosphodiesterase type 5 (PDE-5) inhibitors 2.VASODILATORS 3.ANDROGENS They have revolutionized the treatment of erectile dysfunction. Caution Caution is needed in patients with cardiovascular disease, anatomical deformation of the penis, e.g. Peyronie’s disease, those with a predisposition to prolonged erection,e.g. in sickle-cell disease. They are contraindicated in patients who are on nitrates and in patients with a previous history of non-arteritic anterior ischaemic optic neuropathy. 1.Phosphodiesterase type 5 (PDE-5) inhibitors SILDENAFIL INDICATION -Erectile dysfunction and Pulmonary hypertension MODE OF ACTION Sildenafil is a phosphodiestearase type 5 inhibitor that works by improving blood flow to the penis. During sexual stimulation ,penile nerve endings and endothelial cells release Nitric oxide. This activates enzyme guanylate cyclase resulting the production of cGMP –A Vasodilator SIDE EFFECTS Headache ,flushin,dyspepsia,priapism and allergic reactions DOSAGE 25mg ,50mg or 100mg(max dose) once daily 1-4 hours before 1.Phosphodiesterase type 5 (PDE-5) inhibitors TADALAFIL Works same as sildenafil PRECAUTIONS Cardiovascular disease, active peptic ulcer, hepatic or renal impairment DOSE 50mg initially as a single dose 1 hour before sexual activity Its effect can last for 24 hours Show us your support by SUBSCRIBING,LIKING and SHARING. Connect with us on our website www.medcrine.com Follow us on twitter @medcrine Telegram at .....